FAM201B

Across TCGA pan-cancer cohorts, FAM201B RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of FAM201B’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where FAM201B RNA is repressed in tumor relative to normal tissue. In most cancer types FAM201B is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

UCEC, KIRP, and HNSC are the cancer types where FAM201B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM201B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	II,III,IV	−0.596	<.001	6	view →
KIRP	All	II,III,IV	+0.406	.002	6	view →
HNSC	Male	IV	+0.222	.023	6	view →
LUAD	Female	All	+0.208	<.001	5	view →
THCA	All	All	−0.202	<.001	5	view →
KICH	Female	All	−0.240	<.001	3	view →
LUSC	All	All	+0.196	.001	3	view →
KIRC	All	All	+0.104	.013	3	view →
PRAD	All	All	−0.096	.046	2	view →
CHOL	All	All	+0.326	.034	1	view →
COAD	All	All	+0.128	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

FAM201B–UCEC

Open the UCEC breakdown →