FAM201B

Across TCGA pan-cancer cohorts, FAM201B RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FAM201B data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher FAM201B RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM201B expression acts as an unfavorable survival marker, although some lineages such as SKCM and OV show a favorable association.

SKCM, OV, and LIHC are the cancer types where FAM201B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	IV	0.836	0.262	<.001	62	view →
OV	DFS	Quartile	All	0.603	0.460	.001	54	view →
LIHC	OS	Tertile	All	0.667	0.816	.003	42	view →
UCEC	DFS	Quartile	All	0.829	0.922	.007	36	view →
PAAD	DFS	Quartile	All	0.596	0.408	.003	30	view →
KIRP	DFS	Median	IV	0.036	0.526	.006	24	view →
THYM	OS	Tertile	All	0.717	0.949	.003	23	view →
ACC	DFS	Tertile	IV	0.656	0.091	.017	22	view →
LUSC	DFS	Quartile	All	0.944	0.658	.002	21	view →
THCA	DFS	Quartile	IV	0.663	0.863	.022	17	view →
ESCA	OS	Median	IV	0.698	0.222	.006	15	view →
GBM	DFS	Tertile	All	0.209	0.335	.026	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FAM201B–SKCM (OS)

Open the SKCM breakdown →