FAM197Y4

Across TCGA patient cohorts, FAM197Y4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,105 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM197Y4-associated GO terms across cancer lineages are Regulation of Arp2/3 complex-mediated actin nucleation, Mitochondrial gene expression, and Response to UV-C. Each is linked with FAM197Y4 in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM197Y4-to-partner and partner-to-FAM197Y4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Arp2/3 complex-mediated actin nucleation grouped by FAM197Y4-low versus FAM197Y4-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM197Y4→partner) and Y-score (partner→FAM197Y4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Regulation of Arp2/3 complex-mediated actin nucleation →	+0.131	+0.007	<.001	.009	2	4
STAD	Mitochondrial gene expression →	+0.146	+0.012	<.001	.001	3	3
STAD	Response to UV-C →	+0.109	+0.018	<.001	.001	3	3
STAD	Negative regulation of ubiquitin protein ligase activity →	+0.101	+0.020	<.001	.004	3	2
STAD	Polyprenol metabolic process →	+0.110	+0.015	<.001	.005	3	2
STAD	Iron-sulfur cluster assembly →	+0.115	+0.022	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

Regulation of Arp2/3 complex-mediated actin nucleation by FAM197Y4 expression — LUSC

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