Q-omics provides the consensus-scored FAM197Y4 profile across patient tissues and cancer cell-line models. FAM197Y4 expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, FAM197Y4 RNA expression shows 3,627 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight HNSC, and ESCA as cancer lineages where FAM197Y4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes FAM197Y4 survival associations across molecular data types. FAM197Y4 RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

FAM197Y4 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	HNSC (153)	view →

This table ranks reproducible FAM197Y4 RNA expression–survival associations across cancer types. High FAM197Y4 expression shows unfavorable associations in HNSC, BLCA, KIRC, SARC and LIHC. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for FAM197Y4 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.183	0.607	<.001	153	view →
BLCA	DFS	Tertile	All	0.224	0.633	<.001	54	view →
KIRC	OS	Tertile	All	0.689	0.884	.002	36	view →
SARC	OS	Tertile	All	0.178	0.772	<.001	36	view →
LIHC	DFS	Tertile	All	0.137	0.559	.001	18	view →

Pink = unfavorable, green = favorable. all 5 lineages →

FAM197Y4-HNSC (DFS)

Kaplan–Meier survival curve for FAM197Y4 RNA expression in HNSC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with FAM197Y4 in patient tissues and cancer cell lines. In patient samples, FAM197Y4 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	3,627	ESCA (2545)	view →
Function (RNA)	1,105	STAD (874)	view →