FAM197Y4

Across TCGA pan-cancer cohorts, FAM197Y4 RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated FAM197Y4 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAM197Y4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM197Y4 expression acts as an unfavorable survival marker.

HNSC, BLCA, and KIRC are the cancer types where FAM197Y4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.183	0.607	<.001	153	view →
BLCA	DFS	Tertile	All	0.224	0.633	<.001	54	view →
KIRC	OS	Tertile	All	0.689	0.884	.002	36	view →
SARC	OS	Tertile	All	0.178	0.772	<.001	36	view →
LIHC	DFS	Tertile	All	0.137	0.559	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FAM197Y4–HNSC (DFS)

Open the HNSC breakdown →