FAM186B

Across TCGA patient cohorts, FAM186B mutation is significantly associated with the RNA expression of many other genes, with 4,298 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM186B-associated genes across cancer lineages are RPS26P30, RNA5SP176, and MIR6870. Each is linked with FAM186B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM186B-to-partner and partner-to-FAM186B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS26P30 grouped by FAM186B-low versus FAM186B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM186B→partner) and Y-score (partner→FAM186B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS26P30 →	+0.118	+4.984	<.001	.005	3	3
UCEC	RNA5SP176 →	+0.245	+3.022	<.001	.005	3	3
UCEC	MIR6870 →	+0.305	+1.981	<.001	.003	3	2
UCEC	TAF9 →	+0.637	+2.058	<.001	<.001	3	2
UCEC	TUBGCP5 →	+0.490	+3.258	<.001	<.001	3	2
UCEC	UHRF1 →	+0.839	+1.788	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,298 associations by consensus.

RPS26P30 by FAM186B expression — LUAD

Explore this box plot interactively →