FAM182B

Across TCGA cell cohorts, FAM182B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM182B-associated genes across cancer lineages are BPIFB6, ADIPOQ, and PRAMEF20. Each is linked with FAM182B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM182B-to-partner and partner-to-FAM182B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by FAM182B-low versus FAM182B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM182B→partner) and Y-score (partner→FAM182B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ADIPOQ →	+0.009	+3.217	<.001	.006	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR2J3 →	+0.032	+3.242	<.001	.003	3	1
LARGE_INTESTINE	TBC1D3K →	+0.252	+3.584	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

BPIFB6 by FAM182B expression — LARGE_INTESTINE

Explore this box plot interactively →