FAM182B

Across TCGA pan-cancer cohorts, FAM182B RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated FAM182B data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher FAM182B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM182B expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

KIRP, MESO, and KICH are the cancer types where FAM182B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.593	0.761	<.001	97	view →
MESO	DFS	Tertile	III,IV	0.245	0.493	<.001	78	view →
KICH	OS	Median	III,IV	0.347	0.942	.001	69	view →
LIHC	OS	Median	All	0.703	0.841	<.001	58	view →
HNSC	DFS	Median	IV	0.718	0.563	.002	50	view →
SKCM	DFS	Tertile	III,IV	0.652	0.344	<.001	46	view →
THYM	DFS	Median	II,III,IV	0.917	0.567	.001	40	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	29	view →
DLBC	DFS	Tertile	III,IV	0.316	0.984	.013	27	view →
BRCA	DFS	Quartile	IV	0.909	0.341	.010	22	view →
COAD	OS	Quartile	III,IV	0.667	0.907	.014	18	view →
UCS	OS	Tertile	IV	0.828	0.543	.036	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

FAM182B–KIRP (DFS)

Open the KIRP breakdown →