FAM182B

Across TCGA cell cohorts, FAM182B mutation is significantly associated with the mutation status of many other genes, with 584 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM182B-associated genes across cancer lineages are DIS3, SPOCK1, and TSPAN33. Each is linked with FAM182B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM182B-to-partner and partner-to-FAM182B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DIS3 grouped by FAM182B-low versus FAM182B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM182B→partner) and Y-score (partner→FAM182B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DIS3 →	+2.630	+3.047	.005	.005	1	2
LARGE_INTESTINE	SPOCK1 →	+3.799	+3.329	.005	.005	1	2
LARGE_INTESTINE	TSPAN33 →	+4.799	+3.672	.002	.002	1	2
LARGE_INTESTINE	ATP2C1 →	+4.215	+3.874	<.001	<.001	1	2
LARGE_INTESTINE	RECQL →	+2.893	+3.222	.003	.003	1	2
LARGE_INTESTINE	AP5B1 →	+3.478	+5.056	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 584 associations by consensus.

DIS3 by FAM182B expression — LARGE_INTESTINE

Explore this box plot interactively →