FAM182A

Across TCGA patient cohorts, FAM182A mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM182A-associated genes across cancer lineages are SSTR5, CCDC197, and RNU6-792P. Each is linked with FAM182A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM182A-to-partner and partner-to-FAM182A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSTR5 grouped by FAM182A-low versus FAM182A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM182A→partner) and Y-score (partner→FAM182A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SSTR5 →	+1.105	+3.871	<.001	.002	3	1
UCEC	CCDC197 →	+0.095	+4.070	.008	.001	3	1
UCEC	RNU6-792P →	+0.245	+4.400	.004	.006	3	1
UCEC	SNORA70E →	+0.323	+3.386	.007	.008	3	1
UCEC	RNU6-376P →	+0.317	+4.132	<.001	.009	3	1
UCEC	MIR521-1 →	+0.300	+4.260	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

SSTR5 by FAM182A expression — UCEC

Explore this box plot interactively →