Across TCGA patient cohorts, FAM180A protein abundance is significantly associated with the RNA expression of many other genes, with 1,349 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAM180A-associated genes across cancer lineages are PAM, IGFBP7, and NIPSNAP1. Each is linked with FAM180A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM180A-to-partner and partner-to-FAM180A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM180A→partner) and Y-score (partner→FAM180A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PAM →	+0.917	+1.458	.009	.001	3	2
LSCC	IGFBP7 →	+1.653	+1.644	.003	.002	3	2
LSCC	NIPSNAP1 →	-0.747	-1.312	.008	.007	3	2
LSCC	MRPS18B →	-0.861	-1.532	.009	.001	3	2
LSCC	DBNDD1 →	-1.161	-1.424	.005	.002	3	2
LSCC	SNTA1 →	-1.132	-0.735	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,349 associations by consensus.

Exploration

FAM180A survival (RNA) · tumor vs normal (RNA) · all FAM180A data types