FAM178B

Across TCGA patient cohorts, FAM178B mutation is significantly associated with the RNA expression of many other genes, with 3,909 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM178B-associated genes across cancer lineages are MICG, RNU6-971P, and LINC02369. Each is linked with FAM178B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM178B-to-partner and partner-to-FAM178B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MICG grouped by FAM178B-low versus FAM178B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM178B→partner) and Y-score (partner→FAM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MICG →	+0.260	+5.969	.002	.002	3	1
CESC	RNU6-971P →	+0.347	+5.306	<.001	.006	3	1
CESC	LINC02369 →	+0.043	+5.812	<.001	.003	3	1
CESC	LINC01872 →	+0.034	+5.812	<.001	.003	3	1
CESC	RNU4-41P →	+0.256	+7.164	<.001	<.001	3	1
CESC	TRAJ29 →	+0.482	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,909 associations by consensus.

MICG by FAM178B expression — CESC

Explore this box plot interactively →