FAM171B

Across TCGA patient cohorts, FAM171B protein abundance is significantly associated with the RNA expression of many other genes, with 3,357 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM171B-associated genes across cancer lineages are GRK3, LGALS1, and PIK3IP1. Each is linked with FAM171B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM171B-to-partner and partner-to-FAM171B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM171B versus GRK3 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171B→partner) and Y-score (partner→FAM171B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GRK3 →	+0.493	+0.440	<.001	<.001	3	1
GBM	LGALS1 →	-0.518	-0.298	.002	.001	3	1
GBM	PIK3IP1 →	+0.528	+0.319	.004	.007	3	1
GBM	SOX10 →	+1.745	+0.468	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.830	+0.441	<.001	<.001	3	1
GBM	TPTEP1 →	+0.980	+0.305	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,357 associations by consensus.

FAM171B vs GRK3 — GBM

Explore this scatter interactively →