FAM171B

Across TCGA patient cohorts, FAM171B mutation is significantly associated with the RNA expression of many other genes, with 2,936 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM171B-associated genes across cancer lineages are RPS29P32, MCAT, and PSMD9. Each is linked with FAM171B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM171B-to-partner and partner-to-FAM171B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by FAM171B-low versus FAM171B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171B→partner) and Y-score (partner→FAM171B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.387	+1.936	<.001	.008	3	3
UCEC	MCAT →	+0.478	+2.917	<.001	<.001	3	3
UCEC	PSMD9 →	+0.440	+1.864	<.001	.004	3	3
UCEC	GNLY →	+0.838	+2.815	.007	.001	3	3
UCEC	ZWINT →	+0.775	+2.403	<.001	.002	3	3
UCEC	AUNIP →	+0.755	+2.592	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,936 associations by consensus.

RPS29P32 by FAM171B expression — UCEC

Explore this box plot interactively →