FAM171B

Across TCGA cell cohorts, FAM171B mutation is significantly associated with the RNA expression of many other genes, with 1,054 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM171B-associated genes across cancer lineages are PRAMEF14, NOB1, and STOX1. Each is linked with FAM171B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM171B-to-partner and partner-to-FAM171B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF14 grouped by FAM171B-low versus FAM171B-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM171B→partner) and Y-score (partner→FAM171B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PRAMEF14 →	+0.139	+2.938	.001	.003	3	2
LARGE_INTESTINE	NOB1 →	+0.532	+2.829	.002	<.001	3	2
LARGE_INTESTINE	STOX1 →	+0.818	+3.082	.005	.007	3	2
LARGE_INTESTINE	TMEM107 →	+0.793	+3.237	.003	.003	3	2
LARGE_INTESTINE	ZNF48 →	+0.513	+2.043	.002	.008	3	2
LARGE_INTESTINE	DNAH10 →	+0.594	+2.043	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,054 associations by consensus.

PRAMEF14 by FAM171B expression — LUNG_SCLC

Explore this box plot interactively →