FAM170B

Across TCGA cell cohorts, FAM170B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM170B-associated genes across cancer lineages are KRTAP8-1, KRTAP19-8, and OR4E2. Each is linked with FAM170B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM170B-to-partner and partner-to-FAM170B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP8-1 grouped by FAM170B-low versus FAM170B-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM170B→partner) and Y-score (partner→FAM170B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	KRTAP8-1 →	+0.150	+5.781	<.001	.001	3	1
BREAST	KRTAP19-8 →	+0.536	+5.169	<.001	.005	3	1
BREAST	OR4E2 →	+0.025	+5.169	<.001	.005	3	1
LARGE_INTESTINE	OR4F4 →	+0.025	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KRTAP8-1 by FAM170B expression — BREAST

Explore this box plot interactively →