FAM167A

Across TCGA patient cohorts, FAM167A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,169 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible FAM167A-associated GO terms across cancer lineages are Regulation of Ras protein signal transduction, Regulation of autophagy of mitochondrion, and Myeloid cell homeostasis. Each is linked with FAM167A in more than 22 cancer types. Because this analysis shows association rather than direction, both FAM167A-to-partner and partner-to-FAM167A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Ras protein signal transduction grouped by FAM167A-low versus FAM167A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM167A→partner) and Y-score (partner→FAM167A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of Ras protein signal transduction →	+0.041	+0.708	<.001	<.001	2	23
GBM	Regulation of autophagy of mitochondrion →	+0.037	+1.065	<.001	<.001	3	21
LAML	Myeloid cell homeostasis →	+0.038	+0.480	<.001	.002	2	22
STAD	Regulation of small GTPase mediated signal transduction →	+0.038	+0.666	<.001	<.001	2	22
UVM	Obsolete selective autophagy →	+0.039	+0.887	<.001	<.001	3	21
TGCT	Regulation of actin filament bundle assembly →	+0.049	+0.972	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

Regulation of Ras protein signal transduction by FAM167A expression — STAD

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