FAM161B

Across TCGA patient cohorts, FAM161B RNA expression is significantly associated with the protein abundance of many other proteins, with 21,644 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FAM161B-associated proteins across cancer lineages are RPL18A_S123, DDAH1, and MTA1_S449. Each is linked with FAM161B in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM161B-to-partner and partner-to-FAM161B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM161B versus RPL18A_S123 in GBM, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161B→partner) and Y-score (partner→FAM161B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL18A_S123 →	-0.578	-0.411	<.001	<.001	3	7
BRCA	DDAH1 →	+0.859	+0.855	<.001	<.001	3	7
PDAC	MTA1_S449 →	+0.458	+0.282	<.001	.003	3	7
GBM	TTC7B →	+0.370	+0.434	<.001	<.001	3	6
CCRCC	ZFYVE1 →	+0.235	+0.437	<.001	<.001	3	6
UCEC	RPS8_T130 →	-0.607	-0.255	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,644 associations by consensus.

FAM161B vs RPL18A_S123 — GBM

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