FAM161B

Across TCGA cell cohorts, FAM161B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,962 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAM161B-associated GO terms across cancer lineages are Establishment of protein localization to plasma membrane, Golgi to plasma membrane protein transport, and 'de novo' UMP biosynthetic process. Each is linked with FAM161B in more than 10 cancer types. Because this analysis shows association rather than direction, both FAM161B-to-partner and partner-to-FAM161B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to plasma membrane grouped by FAM161B-low versus FAM161B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161B→partner) and Y-score (partner→FAM161B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Establishment of protein localization to plasma membrane →	+0.126	+0.764	<.001	.004	3	11
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.136	+0.786	.003	.001	3	10
BONE	'de novo' UMP biosynthetic process →	-0.156	-0.871	.001	<.001	3	10
STOMACH	Macroautophagy →	+0.082	+0.784	.001	.003	3	9
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.150	+0.552	.007	.009	3	9
BONE	Mitochondrial tRNA pseudouridine synthesis →	-0.111	-0.593	.003	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,962 associations by consensus.

Establishment of protein localization to plasma membrane by FAM161B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →