FAM161B

Across TCGA cell cohorts, FAM161B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM161B-associated genes across cancer lineages are LCE1F, SMIM28, and C14orf177. Each is linked with FAM161B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM161B-to-partner and partner-to-FAM161B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by FAM161B-low versus FAM161B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM161B→partner) and Y-score (partner→FAM161B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCE1F →	+0.165	+5.415	<.001	.004	3	1
CNS	SMIM28 →	+0.046	+5.321	<.001	.005	3	1
BLOOD_Leukemia	C14orf177 →	+0.069	+4.922	<.001	.009	3	1
BLOOD_Leukemia	RBMY1D →	+0.239	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

LCE1F by FAM161B expression — LARGE_INTESTINE

Explore this box plot interactively →