FAM13B

Across TCGA cell cohorts, FAM13B mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM13B-associated genes across cancer lineages are DTHD1, WDR87, and OR6K3. Each is linked with FAM13B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM13B-to-partner and partner-to-FAM13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DTHD1 grouped by FAM13B-low versus FAM13B-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM13B→partner) and Y-score (partner→FAM13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DTHD1 →	+0.056	+5.087	<.001	.004	3	2
LARGE_INTESTINE	WDR87 →	+0.016	+3.353	.002	.004	3	2
OESOPHAGUS	OR6K3 →	+0.006	+4.906	<.001	.006	3	1
LARGE_INTESTINE	GHRHR →	+0.043	+2.791	.005	.005	3	1
LARGE_INTESTINE	GALR3 →	+0.111	+3.865	<.001	.001	3	1
LARGE_INTESTINE	KLHDC7B →	+0.551	+3.707	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

DTHD1 by FAM13B expression — URINARY_TRACT

Explore this box plot interactively →