FAM13A

Across TCGA cell cohorts, FAM13A mutation is significantly associated with the RNA expression of many other genes, with 256 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM13A-associated genes across cancer lineages are AVPR1B, EIF3L, and DEPDC5. Each is linked with FAM13A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM13A-to-partner and partner-to-FAM13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVPR1B grouped by FAM13A-low versus FAM13A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM13A→partner) and Y-score (partner→FAM13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AVPR1B →	+0.009	+4.415	<.001	.007	3	1
LARGE_INTESTINE	EIF3L →	+0.550	+3.087	.002	.006	3	1
LARGE_INTESTINE	DEPDC5 →	+0.630	+3.169	.001	.009	3	1
LARGE_INTESTINE	HMGXB4 →	+0.562	+3.364	.004	.002	3	1
LARGE_INTESTINE	TNRC6B →	+0.743	+3.364	.001	.002	3	1
LARGE_INTESTINE	PARD6A →	+0.825	+3.451	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

AVPR1B by FAM13A expression — SKIN

Explore this box plot interactively →