FAM138E

Across TCGA pan-cancer cohorts, FAM138E RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FAM138E’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where FAM138E RNA is repressed in tumor relative to normal tissue. In most cancer types FAM138E is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

BLCA are the cancer types where FAM138E tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM138E RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−0.118	.022	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

FAM138E–BLCA

Open the BLCA breakdown →