Across TCGA patient cohorts, FAM138C mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM138C-associated genes across cancer lineages are OR6C70, RNU6-1155P, and RNU6-497P. Each is linked with FAM138C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM138C-to-partner and partner-to-FAM138C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM138C→partner) and Y-score (partner→FAM138C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR6C70 →	+0.085	+5.551	.002	.004	3	1
UCEC	RNU6-1155P →	+0.604	+8.060	<.001	<.001	3	1
UCEC	RNU6-497P →	+0.573	+5.358	<.001	.006	3	1
UCEC	CCL27 →	+0.152	+7.470	<.001	<.001	3	1
UCEC	RN7SKP216 →	+0.306	+5.621	.001	.004	3	1
UCEC	SEPTIN14P24 →	+0.359	+5.621	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

FAM138C survival (RNA) · tumor vs normal (RNA) · all FAM138C data types