FAM122C

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM122C RNA expression is significantly associated with the protein abundance of many other proteins, with 11,476 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM122C-associated proteins across cancer lineages are NUB1, FAM122B_S50, and HCFC1. Each is linked with FAM122C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM122C-to-partner and partner-to-FAM122C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM122C versus NUB1 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122C→partner) and Y-score (partner→FAM122C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCNUB1 →+0.392+0.492<.001<.00135
HNSCFAM122B_S50 →+0.695+0.795<.001<.00134
HNSCHCFC1 →+0.283+0.546<.001<.00134
HNSCYWHAZ →-0.288-0.399<.001.00234
LUADPSMB5 →-0.372-0.323<.001<.00134
LSCCPHF6 →+0.408+0.342.002.00334
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,476 associations by consensus.

FAM122C vs NUB1 — HNSC

Per-sample scatter of FAM122C vs NUB1 in HNSC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration