FAM122C

Across TCGA patient cohorts, FAM122C mutation is significantly associated with the RNA expression of many other genes, with 1,050 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM122C-associated genes across cancer lineages are RNU1-68P, MIR4727, and RNA5SP436. Each is linked with FAM122C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM122C-to-partner and partner-to-FAM122C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-68P grouped by FAM122C-low versus FAM122C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122C→partner) and Y-score (partner→FAM122C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-68P →	+0.054	+2.818	<.001	.008	3	2
BLCA	MIR4727 →	+0.575	+4.899	<.001	.005	3	2
UCEC	RNA5SP436 →	+0.229	+2.352	<.001	.008	3	2
UCEC	RNA5SP410 →	+0.525	+1.711	<.001	.004	3	2
UCEC	SEPSECS-AS1 →	+0.274	+1.874	.001	.002	3	1
UCEC	LAMTOR1 →	+0.281	+1.885	.008	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,050 associations by consensus.

RNU1-68P by FAM122C expression — UCEC

Explore this box plot interactively →