FAM122C

Across TCGA cell cohorts, FAM122C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,652 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FAM122C-associated GO terms across cancer lineages are Macroautophagy, Regulation of organelle assembly, and Protein polyubiquitination. Each is linked with FAM122C in more than 13 cancer types. Because this analysis shows association rather than direction, both FAM122C-to-partner and partner-to-FAM122C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by FAM122C-low versus FAM122C-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM122C→partner) and Y-score (partner→FAM122C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.064	+0.907	.003	.006	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.038	+1.007	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.060	+1.202	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.072	+0.715	.008	.005	3	13
BREAST	Negative regulation of myoblast fusion →	+0.112	+1.159	<.001	<.001	3	12
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.115	+1.323	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,652 associations by consensus.

Macroautophagy by FAM122C expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →