Across TCGA patient cohorts, FAM120C protein abundance is significantly associated with the RNA expression of many other genes, with 10,007 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM120C-associated genes across cancer lineages are PPP1R3F, ZC3H6, and ZMAT1. Each is linked with FAM120C in more than 6 cancer types. Because this analysis shows association rather than direction, both FAM120C-to-partner and partner-to-FAM120C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120C→partner) and Y-score (partner→FAM120C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPP1R3F →	+0.608	+0.347	<.001	<.001	3	7
HNSC	ZC3H6 →	+0.711	+0.359	<.001	<.001	3	6
OV	ZMAT1 →	+1.374	+0.337	<.001	.005	2	6
OV	ZBED2 →	-1.391	-0.392	.006	.001	3	5
OV	GSPT2 →	+1.002	+0.363	.001	.004	3	5
HNSC	RN7SL762P →	+0.586	+0.236	.006	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,007 associations by consensus.

Exploration

FAM120C survival (RNA) · tumor vs normal (RNA) · all FAM120C data types