Across TCGA patient cohorts, FAM120C mutation is significantly associated with the RNA expression of many other genes, with 4,400 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM120C-associated genes across cancer lineages are NCLN, NOP10, and RPL23AP82. Each is linked with FAM120C in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM120C-to-partner and partner-to-FAM120C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120C→partner) and Y-score (partner→FAM120C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCLN →	+0.378	+2.108	.001	.002	3	3
UCEC	NOP10 →	+0.437	+2.459	<.001	<.001	3	3
UCEC	RPL23AP82 →	+0.426	+1.964	<.001	<.001	3	3
UCEC	BLM →	+0.490	+1.736	<.001	<.001	3	3
UCEC	MFSD12 →	+0.348	+2.970	.002	<.001	3	3
UCEC	SAAL1 →	+0.477	+3.098	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,400 associations by consensus.

Exploration

FAM120C survival (RNA) · tumor vs normal (RNA) · all FAM120C data types