Across TCGA cell cohorts, FAM120C mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM120C-associated genes across cancer lineages are OR56A5, TECTB, and OR1L4. Each is linked with FAM120C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM120C-to-partner and partner-to-FAM120C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120C→partner) and Y-score (partner→FAM120C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.045	+4.736	<.001	.009	3	2
OESOPHAGUS	TECTB →	+0.006	+3.857	<.001	.002	3	1
OESOPHAGUS	OR1L4 →	+0.023	+3.392	.006	.007	3	1
OESOPHAGUS	SCYGR2 →	+0.102	+3.857	<.001	.002	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.179	+4.867	<.001	.009	3	1
OVARY	FGF6 →	+0.066	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

FAM120C survival (RNA) · tumor vs normal (RNA) · all FAM120C data types