FAM120A

Across TCGA cell cohorts, FAM120A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,042 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FAM120A-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, Positive regulation of mRNA 3'-end processing, and Regulation of chromatin organization. Each is linked with FAM120A in more than 14 cancer types. Because this analysis shows association rather than direction, both FAM120A-to-partner and partner-to-FAM120A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by FAM120A-low versus FAM120A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120A→partner) and Y-score (partner→FAM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Proteasome regulatory particle assembly →	+0.123	+0.784	<.001	<.001	3	15
OESOPHAGUS	Positive regulation of mRNA 3'-end processing →	+0.217	+0.910	<.001	<.001	3	14
OVARY	Regulation of chromatin organization →	+0.091	+1.057	<.001	<.001	3	13
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.106	+0.648	.005	.004	3	12
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.050	+0.691	<.001	.007	3	11
OVARY	Regulation of mitotic cytokinesis →	+0.106	+0.741	.003	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,042 associations by consensus.

Proteasome regulatory particle assembly by FAM120A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →