FAM117A

Across TCGA patient cohorts, FAM117A protein abundance is significantly associated with the RNA expression of many other genes, with 7,240 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FAM117A-associated genes across cancer lineages are COLCA1, CPQ, and RGN. Each is linked with FAM117A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM117A-to-partner and partner-to-FAM117A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM117A versus COLCA1 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM117A→partner) and Y-score (partner→FAM117A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	COLCA1 →	+1.316	+0.256	<.001	.005	3	3
UCEC	CPQ →	+0.820	+0.389	.001	.001	3	2
LUAD	RGN →	+0.917	+0.499	.001	<.001	3	2
GBM	LY96 →	+1.796	+0.856	.009	.003	3	2
LUAD	FCER1A →	+0.996	+0.420	.007	.001	3	2
UCEC	MAGEH1 →	+0.907	+0.287	.004	.009	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,240 associations by consensus.

FAM117A vs COLCA1 — LSCC

Explore this scatter interactively →