FAM111A-DT

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM111A-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,481 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM111A-DT-associated proteins across cancer lineages are FAM111A, THUMPD1, and PSMB5. Each is linked with FAM111A-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM111A-DT-to-partner and partner-to-FAM111A-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM111A-DT versus FAM111A in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM111A-DT→partner) and Y-score (partner→FAM111A-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMFAM111A →+0.321+0.317<.001<.00135
BRCATHUMPD1 →+0.326+0.598<.001<.00135
LUADPSMB5 →-0.422-0.407.001.00125
CCRCCPSMB6 →-0.402-0.306<.001.00334
GBMCPSF7 →+0.323+0.349.001.00134
LUADRPL14 →-0.420-0.478<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,481 associations by consensus.

FAM111A-DT vs FAM111A — GBM

Per-sample scatter of FAM111A-DT vs FAM111A in GBM (Pearson r = 0.42).

Explore this scatter interactively →

Exploration