FAM111A-DT

Across TCGA pan-cancer cohorts, FAM111A-DT RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FAM111A-DT data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FAM111A-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated FAM111A-DT expression acts as an unfavorable survival marker, although some lineages such as BLCA and THCA show a favorable association.

BLCA, LGG, and LIHC are the cancer types where FAM111A-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	II,III,IV	0.793	0.620	<.001	60	view →
LGG	OS	Median	All	0.729	0.890	<.001	54	view →
LIHC	DFS	Quartile	All	0.358	0.506	.006	26	view →
PAAD	OS	Quartile	All	0.250	0.658	.002	23	view →
THCA	OS	Quartile	All	1.000	0.878	.004	23	view →
KIRC	DFS	Tertile	All	0.704	0.559	.003	21	view →
SKCM	OS	Tertile	All	0.826	0.731	.012	20	view →
KICH	DFS	Quartile	II,III,IV	0.566	1.000	.006	18	view →
SARC	OS	Median	All	0.879	0.793	.009	18	view →
BRCA	DFS	Quartile	All	0.956	0.916	.016	15	view →
DLBC	DFS	Median	All	0.629	0.915	.012	11	view →
READ	DFS	Tertile	IV	0.316	0.795	.005	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FAM111A-DT–BLCA (OS)

Open the BLCA breakdown →