FAM107B

Across TCGA patient cohorts, FAM107B mutation is significantly associated with the RNA expression of many other genes, with 1,244 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM107B-associated genes across cancer lineages are RPL12P3, SRSF6P1, and YWHAQP9. Each is linked with FAM107B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM107B-to-partner and partner-to-FAM107B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL12P3 grouped by FAM107B-low versus FAM107B-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM107B→partner) and Y-score (partner→FAM107B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RPL12P3 →	+0.250	+7.276	<.001	<.001	3	2
CESC	SRSF6P1 →	+0.063	+4.969	<.001	.004	3	2
COAD	YWHAQP9 →	+0.107	+7.741	.005	.009	3	2
LUSC	SPDYE9 →	+0.016	+4.792	<.001	.006	3	2
LUAD	LINC01745 →	+0.237	+5.157	<.001	.007	3	2
UCEC	IFI27L1 →	+0.476	+3.343	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,244 associations by consensus.

RPL12P3 by FAM107B expression — READ

Explore this box plot interactively →