FAM104B

Across TCGA patient cohorts, FAM104B mutation is significantly associated with the RNA expression of many other genes, with 110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM104B-associated genes across cancer lineages are RNA5SP454, RNA5SP26, and RNU6-1093P. Each is linked with FAM104B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM104B-to-partner and partner-to-FAM104B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP454 grouped by FAM104B-low versus FAM104B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM104B→partner) and Y-score (partner→FAM104B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP454 →	+0.298	+7.640	<.001	.009	3	2
UCEC	RNA5SP26 →	+0.218	+4.245	<.001	.006	3	2
SKCM	RNU6-1093P →	+0.609	+5.292	<.001	.006	3	2
LUSC	RNU7-55P →	+0.603	+4.882	<.001	.005	3	2
SKCM	IFNA17 →	+0.123	+5.867	.003	.003	3	1
SKCM	PCNPP4 →	+0.071	+5.037	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 110 associations by consensus.

RNA5SP454 by FAM104B expression — BLCA

Explore this box plot interactively →