FAM102A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM102A mutation is significantly associated with the RNA expression of many other genes, with 1,124 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM102A-associated genes across cancer lineages are MIR584, RNA5SP468, and FTMT. Each is linked with FAM102A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM102A-to-partner and partner-to-FAM102A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR584 grouped by FAM102A-low versus FAM102A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM102A→partner) and Y-score (partner→FAM102A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR584 →+0.289+3.258.001.00233
BLCARNA5SP468 →+0.874+4.642<.001.00432
KIRPFTMT →+0.069+4.967<.001.00932
STADRNU1-35P →+0.946+4.401<.001.00632
UCECUFSP2 →+0.517+2.743.003.00332
UCECMRPL18 →+0.411+3.345.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,124 associations by consensus.

MIR584 by FAM102A expression — COAD

Box plot of MIR584 in FAM102A-low vs FAM102A-high samples in COAD.

Explore this box plot interactively →

Exploration