FAM102A

Across TCGA pan-cancer cohorts, FAM102A RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of FAM102A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FAM102A RNA is repressed in tumor relative to normal tissue. In most cancer types FAM102A is over-expressed in tumor, although a few such as KIRC and BLCA show the opposite, repressed pattern.

KIRC, LUAD, and BLCA are the cancer types where FAM102A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM102A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−1.733	<.001	11	view →
LUAD	All	III,IV	+0.820	<.001	9	view →
BLCA	All	All	−0.796	<.001	9	view →
LUSC	All	II,III,IV	+1.153	<.001	8	view →
THCA	Female	All	−0.765	<.001	8	view →
COAD	Female	II,III,IV	−0.674	<.001	8	view →
BRCA	All	III,IV	+1.479	<.001	6	view →
KICH	Female	All	+0.958	<.001	6	view →
UCEC	All	All	−1.028	<.001	4	view →
KIRP	All	All	−0.833	<.001	3	view →
CHOL	All	All	+0.967	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

FAM102A–KIRC

Open the KIRC breakdown →