FAM102A

Across TCGA patient cohorts, FAM102A mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM102A-associated genes across cancer lineages are NF2, GAPDH, and ATM. Each is linked with FAM102A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM102A-to-partner and partner-to-FAM102A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF2 grouped by FAM102A-low versus FAM102A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM102A→partner) and Y-score (partner→FAM102A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NF2 →	+0.222	+2.820	.027	.035	3	2
UCEC	GAPDH →	+0.827	+3.169	.004	.018	3	2
UCEC	ATM →	-1.006	-3.169	<.001	.020	3	2
COAD	INPP4B →	-0.384	-2.991	.047	.036	3	1
UCEC	EGFR_pY1068 →	-0.325	-3.169	.018	.020	3	1
UCEC	Notch1 →	+0.203	+2.820	.008	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

NF2 by FAM102A expression — COAD

Explore this box plot interactively →