FAM102A

Across TCGA cell cohorts, FAM102A mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM102A-associated genes across cancer lineages are ODF1, ZIC3, and CTRB2. Each is linked with FAM102A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM102A-to-partner and partner-to-FAM102A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by FAM102A-low versus FAM102A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM102A→partner) and Y-score (partner→FAM102A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ODF1 →	+0.061	+3.944	.002	.006	3	1
BLOOD_Leukemia	ZIC3 →	+0.015	+4.060	<.001	.003	3	1
BLOOD_Leukemia	CTRB2 →	+0.133	+3.855	<.001	.007	3	1
BLOOD_Leukemia	LCE1E →	+0.556	+4.037	<.001	.004	3	1
BLOOD_Leukemia	SLC5A8 →	+0.111	+4.786	<.001	<.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ODF1 by FAM102A expression — BLOOD_Leukemia

Explore this box plot interactively →