FABP4

Across TCGA patient cohorts, FABP4 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP4-associated genes across cancer lineages are MTA2, BTG3P1, and H2AB3. Each is linked with FABP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP4-to-partner and partner-to-FABP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTA2 grouped by FABP4-low versus FABP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP4→partner) and Y-score (partner→FABP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTA2 →	+0.556	+3.234	.003	.009	3	1
SKCM	BTG3P1 →	+0.089	+7.816	<.001	.008	3	1
SKCM	H2AB3 →	+0.109	+7.816	<.001	.008	3	1
UCEC	MIR7702 →	+0.373	+5.060	<.001	.001	3	1
UCEC	STMN1P1 →	+0.491	+3.330	.002	.009	3	1
COAD	RNU105C →	+0.427	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

MTA2 by FABP4 expression — UCEC

Explore this box plot interactively →