FABP4

Across TCGA pan-cancer cohorts, FABP4 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of FABP4’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FABP4 RNA is repressed in tumor relative to normal tissue. In most cancer types FABP4 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, LUAD, and KIRP are the cancer types where FABP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FABP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−4.947	<.001	11	view →
LUAD	Female	III,IV	−6.332	<.001	9	view →
KIRP	Male	III,IV	−3.219	<.001	9	view →
COAD	Female	II,III,IV	−2.635	<.001	9	view →
LIHC	All	III,IV	+1.991	<.001	9	view →
LUSC	Female	II,III,IV	−5.652	<.001	8	view →
STAD	All	All	−2.315	<.001	8	view →
BRCA	All	III,IV	−6.046	<.001	6	view →
UCEC	All	IV	−2.415	.010	4	view →
READ	All	All	−3.583	<.001	3	view →
BLCA	All	All	−2.484	.008	2	view →
KIRC	All	III,IV	−0.908	.021	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

FABP4–THCA

Open the THCA breakdown →