FABP4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FABP4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FABP4-associated genes across cancer lineages are Myosin-IIa_pS1943 and VEGFR2. Each is linked with FABP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FABP4-to-partner and partner-to-FABP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa_pS1943 grouped by FABP4-low versus FABP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FABP4→partner) and Y-score (partner→FABP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMyosin-IIa_pS1943 →+0.254+2.820.045.03631
UCECVEGFR2 →+0.378+2.820.038.03611
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Myosin-IIa_pS1943 by FABP4 expression — UCEC

Box plot of Myosin-IIa_pS1943 in FABP4-low vs FABP4-high samples in UCEC.

Explore this box plot interactively →

Exploration