F9

Across TCGA cell cohorts, F9 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible F9-associated genes across cancer lineages are INSL5, C5orf52, and CASP12. Each is linked with F9 in more than 1 cancer types. Because this analysis shows association rather than direction, both F9-to-partner and partner-to-F9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSL5 grouped by F9-low versus F9-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F9→partner) and Y-score (partner→F9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	INSL5 →	+0.048	+4.467	.001	.004	3	1
SKIN	C5orf52 →	+0.046	+4.415	<.001	.007	3	1
SKIN	CASP12 →	+0.069	+4.095	<.001	.009	3	1
SKIN	KRTAP4-11 →	+0.014	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

INSL5 by F9 expression — SKIN

Explore this box plot interactively →