F9

Across TCGA pan-cancer cohorts, F9 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of F9’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where F9 RNA is repressed in tumor relative to normal tissue. In most cancer types F9 is over-expressed in tumor, although a few such as LIHC and CHOL show the opposite, repressed pattern.

LIHC, CHOL, and KIRC are the cancer types where F9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in F9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	−3.090	<.001	9	view →
CHOL	Female	All	−8.683	<.001	5	view →
KIRC	All	III,IV	−0.003	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

F9–LIHC

Open the LIHC breakdown →