F13B

Across TCGA patient cohorts, F13B mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible F13B-associated genes across cancer lineages are ASNS, C-Raf, and JNK_pT183_Y185. Each is linked with F13B in more than 2 cancer types. Because this analysis shows association rather than direction, both F13B-to-partner and partner-to-F13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by F13B-low versus F13B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F13B→partner) and Y-score (partner→F13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASNS →	+0.467	+2.000	.019	.031	3	3
UCEC	C-Raf →	+0.147	+1.415	<.001	.010	3	3
UCEC	JNK_pT183_Y185 →	-0.140	-1.401	.007	.010	3	3
UCEC	Cyclin-B1 →	+0.479	+1.415	.005	.010	3	3
LUSC	ACC_pS79 →	+0.385	+1.709	.003	.026	3	2
LUSC	ACC1 →	+0.437	+2.584	.007	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

ASNS by F13B expression — LUAD

Explore this box plot interactively →