F13A1

Across TCGA patient cohorts, F13A1 mutation is significantly associated with the RNA expression of many other genes, with 4,733 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible F13A1-associated genes across cancer lineages are AUNIP, SNRPA1, and RN7SL134P. Each is linked with F13A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both F13A1-to-partner and partner-to-F13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AUNIP grouped by F13A1-low versus F13A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F13A1→partner) and Y-score (partner→F13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AUNIP →	+0.602	+1.882	<.001	.001	3	4
UCEC	SNRPA1 →	+0.460	+2.214	<.001	<.001	3	4
CESC	RN7SL134P →	+0.170	+3.874	<.001	.006	3	4
PRAD	PDE4DIPP8 →	+0.054	+5.109	<.001	.008	3	4
HNSC	GPC5-IT1 →	+0.095	+3.226	<.001	.009	3	3
UCEC	COX5A →	+0.323	+1.817	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,733 associations by consensus.

AUNIP by F13A1 expression — UCEC

Explore this box plot interactively →