F13A1

Across TCGA pan-cancer cohorts, F13A1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of F13A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where F13A1 RNA is repressed in tumor relative to normal tissue. In most cancer types F13A1 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KICH, BLCA, and COAD are the cancer types where F13A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in F13A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.590	<.001	11	view →
BLCA	Male	All	−2.437	<.001	11	view →
COAD	Male	All	−2.089	<.001	10	view →
LIHC	Female	All	+1.105	<.001	7	view →
KIRP	All	All	−1.265	<.001	6	view →
BRCA	All	II,III,IV	−0.796	<.001	6	view →
LUSC	All	II,III,IV	−1.372	<.001	5	view →
STAD	All	All	−1.280	<.001	4	view →
CHOL	All	All	+2.143	.002	3	view →
HNSC	Female	All	+1.604	.006	3	view →
READ	All	All	−2.059	.012	2	view →
UCEC	All	All	−0.818	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

F13A1–KICH

Open the KICH breakdown →