F10

Across TCGA cell cohorts, F10 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible F10-associated genes across cancer lineages are RBMY1J, EDDM3A, and TBC1D21. Each is linked with F10 in more than 1 cancer types. Because this analysis shows association rather than direction, both F10-to-partner and partner-to-F10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1J grouped by F10-low versus F10-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F10→partner) and Y-score (partner→F10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RBMY1J →	+0.017	+4.807	<.001	.003	3	2
SKIN	EDDM3A →	+0.032	+5.415	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FAM153B →	+0.589	+3.618	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	OR6Q1 →	+0.012	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

RBMY1J by F10 expression — OVARY

Explore this box plot interactively →