F10

Across TCGA pan-cancer cohorts, F10 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated F10 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher F10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated F10 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

BLCA, LUSC, and PAAD are the cancer types where F10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	II,III,IV	0.306	0.557	.001	91	view →
LUSC	OS	Median	All	0.307	0.466	<.001	69	view →
PAAD	DFS	Tertile	All	0.361	0.150	<.001	46	view →
LGG	DFS	Tertile	All	0.321	0.557	<.001	26	view →
STAD	DFS	Quartile	III,IV	0.188	0.561	.005	21	view →
HNSC	DFS	Quartile	IV	0.432	0.270	.007	20	view →
READ	DFS	Tertile	All	0.338	0.845	.004	20	view →
CHOL	DFS	Median	II,III,IV	0.107	0.510	.017	14	view →
KIRC	DFS	Median	IV	0.752	0.408	.006	12	view →
UCS	DFS	Median	II,III,IV	0.590	0.290	.015	12	view →
SKCM	OS	Quartile	All	0.237	0.424	<.001	11	view →
ACC	DFS	Median	All	0.616	0.184	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

F10–BLCA (OS)

Open the BLCA breakdown →